The Science of Gratitude

Miriam Dineen, ​MMS, PA-C, CAQ-Psych

Psychiatric Physician Assistant

As we gather for Thanksgiving, we look forward to savoring favorite recipes and delicious food, including the tryptophan-rich turkey often associated with boosting our mood. But did you know that the tradition of reflecting on what we are grateful for is even more powerful? Gratitude isn’t only a feel-good practice; it literally reshapes the brain.

When we intentionally pause to notice what we’re thankful for, we activate the prefrontal cortex, which is the region of the brain responsible for emotional regulation, decision-making, and connection. Gratitude also quiets the amygdala, the brain’s built-in alarm system, reducing anxiety and gently shifting us out of fight-or-flight. Over time, practicing gratitude strengthens neural pathways linked to calm, focus, and resilience. It even boosts dopamine and serotonin, the neurotransmitters associated with happiness, motivation, and overall well-being. So this year, as you’re going around the table and naming what you’re grateful for, you can smile knowing your brain is soaking up the benefits.

Banyan Friendsgiving 2025

​As we head into the holiday season, let’s take a few intentional moments each day this week (and beyond!) to notice what’s going well, to appreciate the small blessings, and to look for what is good and hopeful. These tiny moments add up, training the brain to default toward steadiness rather than stress. At Banyan we are wishing you a Thanksgiving filled with peace, connection, and a renewed sense of wellbeing.